A DNA-based Three-state Device
نویسندگان
چکیده
A simple DNA-based nanomechanical device is presented which can be switched between three different conformations by the addition of appropriate signal molecules. Two of these conformations are mechanically rigid. The device consists of two arms formed by double-stranded DNA, connected by a singlestranded hinge. The device can be in a closed or stretched configuration, and in an intermediate relaxed state. The operation of the device is monitored by fluorescence resonance energy transfer and gel electrophoresis experiments. The closing of the supramolecular arms is affected by the salt concentration, probably due to electrostatic interactions of the device with itself.
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